EXFOLIATIVE SYNDROME
\ɛksfˈə͡ʊli͡ətˌɪv sˈɪndɹə͡ʊm], \ɛksfˈəʊliətˌɪv sˈɪndɹəʊm], \ɛ_k_s_f_ˈəʊ_l_iə_t_ˌɪ_v s_ˈɪ_n_d_ɹ_əʊ_m]\
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The deposition of flaky, translucent fibrillar material most conspicuous on the anterior lens capsule and pupillary margin but also in both surfaces of the iris, the zonules, trabecular meshwork, ciliary body, corneal endothelium, and orbital blood vessels. It sometimes forms a membrane on the anterior iris surface. Exfoliation refers to the shedding of pigment by the iris. (Newell, Ophthalmology, 7th ed, p380)
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.