Definitions of exacerbation

1. action that makes a problem or a disease ( or its symptoms) worse; " the aggravation of her condition resulted from lack of care"

2. violent and bitter exasperation; " his foolishness was followed by an exacerbation of their quarrel"

3. The act rendering more violent or bitter; the state of being exacerbated or intensified in violence or malignity; as, exacerbation of passion.

4. The act of exascerbating; increase of malignity; s periodical increase of violence in the course of a disease; increased severity.

5. The act of irritating highly; increase of violence in a disease.