EPIDERMAL GROWTH FACTOR RELATED TRANSFORMING GROWTH FACTOR
\ˌɛpɪdˈɜːmə͡l ɡɹˈə͡ʊθ fˈaktə ɹɪlˈe͡ɪtɪd tɹansfˈɔːmɪŋ ɡɹˈə͡ʊθ fˈaktə], \ˌɛpɪdˈɜːməl ɡɹˈəʊθ fˈaktə ɹɪlˈeɪtɪd tɹansfˈɔːmɪŋ ɡɹˈəʊθ fˈaktə], \ˌɛ_p_ɪ_d_ˈɜː_m_əl ɡ_ɹ_ˈəʊ_θ f_ˈa_k_t_ə ɹ_ɪ_l_ˈeɪ_t_ɪ_d t_ɹ_a_n_s_f_ˈɔː_m_ɪ_ŋ ɡ_ɹ_ˈəʊ_θ f_ˈa_k_t_ə]\
Definitions of EPIDERMAL GROWTH FACTOR RELATED TRANSFORMING GROWTH FACTOR
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Factor isolated in a variety of tissues including epithelium, and maternal decidua. It is closely related to EPIDERMAL GROWTH FACTOR and binds to the EGF receptor. TGF-alpha acts synergistically with TGF-beta in inducing phenotypic transformation, but its physiological role is unknown.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.
Nearby Words
- epidermal growth factor
- epidermal growth factor receptor
- epidermal growth factor receptor genes
- epidermal growth factor receptor kinase
- epidermal growth factor receptor protein tyrosine kinase
- Epidermal Growth Factor Related Transforming Growth Factor
- epidermal growth factor urogastrone
- epidermal growth factors
- epidermal, epidermic
- epidermal, epidermic method
- epidermata