EPIDERMAL GROWTH FACTOR
\ˌɛpɪdˈɜːmə͡l ɡɹˈə͡ʊθ fˈaktə], \ˌɛpɪdˈɜːməl ɡɹˈəʊθ fˈaktə], \ˌɛ_p_ɪ_d_ˈɜː_m_əl ɡ_ɹ_ˈəʊ_θ f_ˈa_k_t_ə]\
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A 6 kD polypeptide growth factor initially discovered in mouse submaxillary glands. Human epidermal growth factor was originally isolated from urine based on its ability to inhibit gastric secretion and called urogastrone. EPIDERMAL GROWTH FACTOR exerts a wide variety of biological effects including the promotion of proliferation and differentiation of mesenchymal and epithelial cells.
By DataStellar Co., Ltd
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.
Nearby Words
- epidermal
- epidermal cell
- epidermal cell derived thymocyte activating factor
- epidermal cyst
- epidermal cysts
- Epidermal Growth Factor
- epidermal growth factor receptor
- epidermal growth factor receptor genes
- epidermal growth factor receptor kinase
- epidermal growth factor receptor protein tyrosine kinase
- epidermal growth factor related transforming growth factor