ENV PROTEIN GP120, HIV
\ˈɛnv pɹˈə͡ʊtiːn d͡ʒˌiːpˈiː wˈɒnhˈʌndɹədən twˈɛnti], \ˈɛnv pɹˈəʊtiːn dʒˌiːpˈiː wˈɒnhˈʌndɹədən twˈɛnti], \ˈɛ_n_v p_ɹ_ˈəʊ_t_iː_n dʒ_ˌiː_p_ˈiː w_ˈɒ_n_h_ˈʌ_n_d_ɹ_ə_d_ə_n t_w_ˈɛ_n_t_i]\
Definitions of ENV PROTEIN GP120, HIV
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External envelope protein of the human immunodeficiency virus which is encoded by the HIV env gene. It has a molecular weight of 120 kD and contains numerous glycosylation sites. Gp120 binds to cells expressing CD4 cell-surface antigens, most notably T4-lymphocytes and monocytes/macrophages. Gp120 has been shown to interfere with the normal function of CD4 and is at least partly responsible for the cytopathic effect of HIV.
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