ENALAPRILIC ACID
\ɛnˌalɐpɹˈɪlɪk ˈasɪd], \ɛnˌalɐpɹˈɪlɪk ˈasɪd], \ɛ_n_ˌa_l_ɐ_p_ɹ_ˈɪ_l_ɪ_k ˈa_s_ɪ_d]\
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The active metabolite of ENALAPRIL and a potent intravenously administered angiotensin-converting enzyme inhibitor. It is an effective agent for the treatment of essential hypertension and has beneficial hemodynamic effects in heart failure. The drug produces renal vasodilation with an increase in sodium excretion.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.