EMMETS OPERATION

\ˈɛmɪts ˌɒpəɹˈe͡ɪʃən], \ˈɛmɪts ˌɒpəɹˈe‍ɪʃən], \ˈɛ_m_ɪ_t_s ˌɒ_p_ə_ɹ_ˈeɪ_ʃ_ə_n]\

Definitions of EMMETS OPERATION

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1898 - American pocket medical dictionary
By Willam Alexander Newman Dorland

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ATP Binding Cassette, Sub Family B Proteins

  • A subfamily transmembrane the superfamily TRANSPORTERS that closely related in GLYCOPROTEIN. When overexpressed, function as dependent efflux pumps able extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing resistance (DRUG RESISTANCE, MULTIPLE). Although P-Glycoproteins share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.
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