EISTEDDFOD

\ˈa͡ɪstɪdfˌɒd], \ˈa‍ɪstɪdfˌɒd], \ˈaɪ_s_t_ɪ_d_f_ˌɒ_d]\
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1914 - Nuttall's Standard dictionary of the English language
By Nuttall, P.Austin.

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ATP Binding Cassette, Sub Family B Proteins

  • A subfamily transmembrane the superfamily TRANSPORTERS that closely related in GLYCOPROTEIN. When overexpressed, function as dependent efflux pumps able extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing resistance (DRUG RESISTANCE, MULTIPLE). Although P-Glycoproteins share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.
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