DUCTAL CARCINOMAS
\dˈʌktə͡l kˌɑːsɪnˈə͡ʊməz], \dˈʌktəl kˌɑːsɪnˈəʊməz], \d_ˈʌ_k_t_əl k_ˌɑː_s_ɪ_n_ˈəʊ_m_ə_z]\
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An invasive (infiltrating) carcinoma of the breast. This carcinoma in which no special histological feature is recognized is designated NOS or Not Otherwise Specified and is by far the most common ductal tumor, accounting for almost 70% of breast cancers. It is characterized by stony hardness upon palpation. It commonly metastasizes to the axillary lymph nodes and its prognosis is the poorest of the various ductal types. (DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1205)
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Word of the day
Procollagen Proline Dioxygenase
- mixed-function oxygenase that catalyzes hydroxylation prolyl-glycyl-containing-peptide, usually in protocollagen, hydroxyprolylglycyl-peptide. The enzyme utilizes molecular oxygen with a concomitant oxidative decarboxylation of 2-oxoglutarate to succinate. EC 1.14.11.2.