DUBIN JOHNSON SYNDROME
\djˈuːbɪn d͡ʒˈɒnsən sˈɪndɹə͡ʊm], \djˈuːbɪn dʒˈɒnsən sˈɪndɹəʊm], \d_j_ˈuː_b_ɪ_n dʒ_ˈɒ_n_s_ə_n s_ˈɪ_n_d_ɹ_əʊ_m]\
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A benign, autosomally recessive inherited hyperbilirubinemia characterized by the presence of a dark pigment in the centrilobular region of the liver cells. There is a functional defect in biliary excretion of bilirubin, cholephilic dyes, and porphyrins. Affected persons may be asymptomatic or have vague constitutional or gastrointestional symptoms. The liver may be slightly enlarged, and oral and intravenous cholangiography fails to visualize the biliary tract.
By DataStellar Co., Ltd
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.
Nearby Words
- dubbin
- dubbing
- dubiate
- dubieties
- dubiety
- Dubin Johnson Syndrome
- dubini's disease
- dubints disease
- dubiosities
- dubiosity
- dubious