DUBIN JOHNSON SYNDROME
\djˈuːbɪn d͡ʒˈɒnsən sˈɪndɹə͡ʊm], \djˈuːbɪn dʒˈɒnsən sˈɪndɹəʊm], \d_j_ˈuː_b_ɪ_n dʒ_ˈɒ_n_s_ə_n s_ˈɪ_n_d_ɹ_əʊ_m]\
Definitions of DUBIN JOHNSON SYNDROME
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A benign, autosomally recessive inherited hyperbilirubinemia characterized by the presence of a dark pigment in the centrilobular region of the liver cells. There is a functional defect in biliary excretion of bilirubin, cholephilic dyes, and porphyrins. Affected persons may be asymptomatic or have vague constitutional or gastrointestional symptoms. The liver may be slightly enlarged, and oral and intravenous cholangiography fails to visualize the biliary tract.
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