DRUM MEMBRANE
\dɹˈʌm mˈɛmbɹe͡ɪn], \dɹˈʌm mˈɛmbɹeɪn], \d_ɹ_ˈʌ_m m_ˈɛ_m_b_ɹ_eɪ_n]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.