DOMINANT IDEA

\dˈɒmɪnənt a͡ɪdˈi͡ə], \dˈɒmɪnənt a‍ɪdˈi‍ə], \d_ˈɒ_m_ɪ_n_ə_n_t aɪ_d_ˈiə]\

Definitions of DOMINANT IDEA

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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