DOLICHYL PHOSPHATE SYNTHETASE
\dˈɒlɪt͡ʃˌɪl fˈɒsfe͡ɪt sˈɪnθɪtˌe͡ɪs], \dˈɒlɪtʃˌɪl fˈɒsfeɪt sˈɪnθɪtˌeɪs], \d_ˈɒ_l_ɪ_tʃ_ˌɪ_l f_ˈɒ_s_f_eɪ_t s_ˈɪ_n_θ_ɪ_t_ˌeɪ_s]\
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An enzyme that, in the pathway of cholesterol biosynthesis, catalyzes the condensation of isopentenyl pyrophosphate and dimethylallylpyrophosphate to yield pyrophosphate and geranylpyrophosphate. The enzyme then catalyzes the condensation of the latter compound with another molecule of isopentenyl pyrophosphate to yield pyrophosphate and farnesylpyrophosphate. EC 2.5.1.1.
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