DIRECTED VERDICT

\da͡ɪɹˈɛktɪd vˈɜːdɪkt], \da‍ɪɹˈɛktɪd vˈɜːdɪkt], \d_aɪ_ɹ_ˈɛ_k_t_ɪ_d v_ˈɜː_d_ɪ_k_t]\

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Proto Oncogene Proteins c erbB 2

  • cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.
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