DIRECTED MOLECULAR EVOLUTION
\da͡ɪɹˈɛktɪd məlˈɛkjʊləɹ ɪvəlˈuːʃən], \daɪɹˈɛktɪd məlˈɛkjʊləɹ ɪvəlˈuːʃən], \d_aɪ_ɹ_ˈɛ_k_t_ɪ_d m_ə_l_ˈɛ_k_j_ʊ_l_ə_ɹ ɪ_v_ə_l_ˈuː_ʃ_ə_n]\
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.