DIGITALIS GLYCOSIDES
\dˌɪd͡ʒɪtˈɑːlis ɡlˈa͡ɪkəsˌa͡ɪdz], \dˌɪdʒɪtˈɑːlis ɡlˈaɪkəsˌaɪdz], \d_ˌɪ_dʒ_ɪ_t_ˈɑː_l_i_s ɡ_l_ˈaɪ_k_ə_s_ˌaɪ_d_z]\
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Glycosides from plants of the genus DIGITALIS. Some of these are useful as cardiotonic and anti-arrhythmia agents. Included also are semi-synthetic derivatives of the naturally occurring glycosides. The term has sometimes been used more broadly to include all CARDIAC GLYCOSIDES, but here is restricted to those related to Digitalis.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.