DIFFERENTIATION ANTIGENS, LEUKOCYTE, HUMAN
\dˌɪfəɹˌɛnʃɪˈe͡ɪʃən ˈantɪd͡ʒˌɛnz], \dˌɪfəɹˌɛnʃɪˈeɪʃən ˈantɪdʒˌɛnz], \d_ˌɪ_f_ə_ɹ_ˌɛ_n_ʃ_ɪ__ˈeɪ_ʃ_ə_n ˈa_n_t_ɪ_dʒ_ˌɛ_n_z]\
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Differentiation antigens residing on mammalian leukocytes. CD stands for cluster of differentiation, which refers to groups of monoclonal antibodies that show similiar reactivity with certain subpopulations of antigens of a particular lineage or differentiation stage. The subpopulations of antigens are also known by the same CD designation.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.