DIFFERENTIATED GENES
\dˌɪfəɹˈɛnʃɪˌe͡ɪtɪd d͡ʒˈiːnz], \dˌɪfəɹˈɛnʃɪˌeɪtɪd dʒˈiːnz], \d_ˌɪ_f_ə_ɹ_ˈɛ_n_ʃ_ɪ__ˌeɪ_t_ɪ_d dʒ_ˈiː_n_z]\
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Genes that code for proteins required for the enzymatic and structural functions of cells. They include developmental and differentiated genes.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.