DES ARGININE COMPLEMENT 5A
\dˈɛs ˈɑːd͡ʒɪnˌa͡ɪn kˈɒmplɪmənt fˈa͡ɪv ˈe͡ɪ], \dˈɛs ˈɑːdʒɪnˌaɪn kˈɒmplɪmənt fˈaɪv ˈeɪ], \d_ˈɛ_s ˈɑː_dʒ_ɪ_n_ˌaɪ_n k_ˈɒ_m_p_l_ɪ_m_ə_n_t f_ˈaɪ_v ˈeɪ]\
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Complement 5a with the carboxy-terminal arginine removed. The arginine is rapidly cleaved from the C5a fragment during complement activation by carboxypeptidase B present in normal human serum. C5a des-Arg shows complete loss of spasmogenic activity though it retains some chemotactic ability.
By DataStellar Co., Ltd
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