DENYS DRASH SYNDROME
\dɪnˈa͡ɪz dɹˈaʃ sˈɪndɹə͡ʊm], \dɪnˈaɪz dɹˈaʃ sˈɪndɹəʊm], \d_ɪ_n_ˈaɪ_z d_ɹ_ˈa_ʃ s_ˈɪ_n_d_ɹ_əʊ_m]\
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A rare syndrome characterized by UROGENITAL ABNORMALITIES, PSEUDOHERMAPHRODITISM, and Wilms tumor (NEPHROBLASTOMA).
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.