DECORTICATE RIGIDITIES
\dɛkˈɔːtɪkˌe͡ɪt ɹɪd͡ʒˈɪdɪtiz], \dɛkˈɔːtɪkˌeɪt ɹɪdʒˈɪdɪtiz], \d_ɛ_k_ˈɔː_t_ɪ_k_ˌeɪ_t ɹ_ɪ_dʒ_ˈɪ_d_ɪ_t_i_z]\
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A condition characterized by abnormal posturing of the limbs that is associated with injury to the brainstem. This may occur as a clinical manifestation or induced experimentally in animals. The extensor reflexes are exaggerated leading to rigid extension of the limbs accompanied by hyperreflexia and opisthotonus. This condition is usually caused by lesions which occur in the region of the brainstem that lies between the red nuclei and the vestibular nuclei. In contrast, decorticate rigidity is characterized by flexion of the elbows and wrists with extension of the legs and feet. The causative lesion for this condition is located above the red nuclei and usually consists of diffuse cerebral damage. (From Adams et al., Principles of Neurology, 6th ed, p358)
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Word of the day
Procollagen Proline Dioxygenase
- mixed-function oxygenase that catalyzes hydroxylation prolyl-glycyl-containing-peptide, usually in protocollagen, hydroxyprolylglycyl-peptide. The enzyme utilizes molecular oxygen with a concomitant oxidative decarboxylation of 2-oxoglutarate to succinate. EC 1.14.11.2.