DEANE, SILAS
\dˈiːn], \dˈiːn], \d_ˈiː_n]\
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(1737-1789), born in Groton, Conn., died in Deal, England. He was a member of the Connecticut Committee of Correspondence, and afterward a Representative in the Continental Congress. In 1776 he was sent to France to purchase supplies for the Confederacy. Vergennes, the French Minister of Foreign Affairs, referred him to Beaumarchais, a secret agent of the French Government, and with him Deane negotiated. He was accused of extravagance and dishonesty, chiefly by his colleague, Arthur Lee. Deane, Lee and Franklin negotiated treaties of amity and commerce with France, which were signed February 6, 1778. Deane was recalled the same year at the instigation of Lee. Congress refused him a hearing for some time and finally required a full statement. Returning to France for the necessary papers, he found himself unpopular there, and had to retire to Holland. He died just as he was re-embarking from England for America in 1789.
By John Franklin Jameson
Word of the day
Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.