DANDY WALKER MALFORMATION
\dˈandi wˈɔːkə mˌalfɔːmˈe͡ɪʃən], \dˈandi wˈɔːkə mˌalfɔːmˈeɪʃən], \d_ˈa_n_d_i w_ˈɔː_k_ə m_ˌa_l_f_ɔː_m_ˈeɪ_ʃ_ə_n]\
Sort: Oldest first
-
A congenital abnormality of the central nervous system marked by failure of the midline structures of the cerebellum to develop, dilation of the fourth ventricle, and upward displacement of the transverse sinuses, tentorium, and torcula. Clinical features include occipital bossing, progressive head enlargement, bulging of anterior fontanelle, papilledema, ataxia, gait disturbances, nystagmus, and intellectual compromise. (From Menkes, Textbook of Child Neurology, 5th ed, pp294-5)
By DataStellar Co., Ltd
Word of the day
Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.