DAI PROTEIN KINASE
\dˌiːˌe͡ɪˈa͡ɪ pɹˈə͡ʊtiːn kˈɪne͡ɪs], \dˌiːˌeɪˈaɪ pɹˈəʊtiːn kˈɪneɪs], \d_ˌiː__ˌeɪ_ˈaɪ p_ɹ_ˈəʊ_t_iː_n k_ˈɪ_n_eɪ_s]\
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A dsRNA-activated cAMP-independent protein serine/threonine kinase that is induced by interferon. In the presence of dsRNA and ATP, eiF-2 kinase autophosphorylates on several serine and threonine residues. The phosphorylated enzyme catalyzes the phosphorylation of the alpha subunit of eIF-2, leading to the inhibition of protein synthesis. EC 2.7.10.-
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