Definitions of d Methorphan

  1. The d- isomer of the codeine analog of LEVORPHANOL. Dextromethorphan shows high affinity binding to several regions of the brain, including the medullary cough center. This compound is a NMDA receptor antagonist ( RECEPTORS, N- METHYL- D- ASPARTATE) and acts as a non- competitive channel blocker. It is used widely as an antitussive agent, and is also used to study the involvement of glutamate receptors in neurotoxicity.