CYTOCHROME P450 11B1
\sˈa͡ɪtəkɹˌə͡ʊm pˈiː fˈɔːhˈʌndɹədən fˈɪfti ɪlˈɛvən bˈiː wˈɒn], \sˈaɪtəkɹˌəʊm pˈiː fˈɔːhˈʌndɹədən fˈɪfti ɪlˈɛvən bˈiː wˈɒn], \s_ˈaɪ_t_ə_k_ɹ_ˌəʊ_m p_ˈiː f_ˈɔː_h_ˈʌ_n_d_ɹ_ə_d_ə_n f_ˈɪ_f_t_i_ ɪ_l_ˈɛ_v_ə_n b_ˈiː w_ˈɒ_n]\
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A steroid hydroxylase system found in adrenal tissues. It catalyzes the 11-hydroxylation of steroids in the presence of molecular oxygen and consists of an NADPH-specific flavoprotein, a non-heme iron protein, and cytochrome P-450. Its deficiency is a cause of congenital adrenal hyperplasia (ADRENAL HYPERPLASIA, CONGENITAL). EC 1.14.15.4.
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