CYTOADHESIN RECEPTORS
\sˈa͡ɪtə͡ʊdhˌɛsɪn ɹɪsˈɛptəz], \sˈaɪtəʊdhˌɛsɪn ɹɪsˈɛptəz], \s_ˈaɪ_t_əʊ_d_h_ˌɛ_s_ɪ_n ɹ_ɪ_s_ˈɛ_p_t_ə_z]\
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A group of INTEGRINS that includes the platelet outer membrane glycoprotein GPIIb-IIIa (PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX) and the vitronectin receptor (RECEPTORS, VITRONECTIN). They play a major role in cell adhesion and serve as receptors for fibronectin, von Willebrand factor, and vitronectin.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.