COSMIC
\kˈɒzmɪk], \kˈɒzmɪk], \k_ˈɒ_z_m_ɪ_k]\
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Pertaining to the universe and the laws which govvern it; orderly, as opposed to chaotic; in astronomy, rising or setting with the sun, as a star.
By William Dodge Lewis, Edgar Arthur Singer
By William Hand Browne, Samuel Stehman Haldeman
Word of the day
ATP Binding Cassette, Sub Family B Proteins
- A subfamily transmembrane the superfamily TRANSPORTERS that closely related in GLYCOPROTEIN. When overexpressed, function as dependent efflux pumps able extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing resistance (DRUG RESISTANCE, MULTIPLE). Although P-Glycoproteins share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.