CORTICOID TYPE II RECEPTORS
\kˈɔːtɪkˌɔ͡ɪd tˈa͡ɪp ɹˌə͡ʊmən tˈuː ɹɪsˈɛptəz], \kˈɔːtɪkˌɔɪd tˈaɪp ɹˌəʊmən tˈuː ɹɪsˈɛptəz], \k_ˈɔː_t_ɪ_k_ˌɔɪ_d t_ˈaɪ_p ɹ_ˌəʊ_m_ə_n_ t_ˈuː ɹ_ɪ_s_ˈɛ_p_t_ə_z]\
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Cytoplasmic proteins that specifically bind glucocorticoids and mediate their cellular effects. The glucocorticoid receptor-glucocorticoid complex acts in the nucleus to induce transcription of DNA. Glucocorticoids were named for their actions on blood glucose concentration, but they have equally important effects on protein and fat metabolism. Cortisol is the most important example.
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international pitch
- the pitch used to tune instruments for concert performances; usually assigns 440 Hz A above middle C