CONFLUENTIA

\kˌɒnfluːˈɛnʃə], \kˌɒnfluːˈɛnʃə], \k_ˌɒ_n_f_l_uː_ˈɛ_n_ʃ_ə]\
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1846 - Medical lexicon: a dictionary of medical science
By Robley Dunglison

Word of the day

ATP Binding Cassette, Sub Family B Proteins

  • A subfamily transmembrane the superfamily TRANSPORTERS that closely related in GLYCOPROTEIN. When overexpressed, function as dependent efflux pumps able extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing resistance (DRUG RESISTANCE, MULTIPLE). Although P-Glycoproteins share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.
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