COMMON ACUTE LYMPHOBLASTIC LEUKEMIA ANTIGENS
\kˈɒmən ɐkjˈuːt lˌɪmfəblˈastɪk luːkˈiːmi͡əɹ ˈantɪd͡ʒˌɛnz], \kˈɒmən ɐkjˈuːt lˌɪmfəblˈastɪk luːkˈiːmiəɹ ˈantɪdʒˌɛnz], \k_ˈɒ_m_ə_n ɐ_k_j_ˈuː_t l_ˌɪ_m_f_ə_b_l_ˈa_s_t_ɪ_k l_uː_k_ˈiː_m_iə_ɹ ˈa_n_t_ɪ_dʒ_ˌɛ_n_z]\
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Enzyme that is a major constituent of kidney brush-border membranes and is also present to a lesser degree in the brain and other tissues. It preferentially catalyzes cleavage at the amino group of hydrophobic residues of the B-chain of insulin as well as opioid peptides and other biologically active peptides. The enzyme is inhibited primarily by EDTA, phosphoramidon, and thiorphan and is reactivated by zinc. Neprilysin is identical to common acute lymphoblastic leukemia antigen (CALLA), an important marker in the diagnosis of human acute lymphocytic leukemia. EC 3.4.24.11.
By DataStellar Co., Ltd
Word of the day
tinctura quininae ammoniata
- A preparation made by dissolving quinin sulphate in alcohol [Br. Ph.].
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