CLOSED COHORT STUDY
\klˈə͡ʊzd kˈə͡ʊhɔːt stˈʌdi], \klˈəʊzd kˈəʊhɔːt stˈʌdi], \k_l_ˈəʊ_z_d k_ˈəʊ_h_ɔː_t s_t_ˈʌ_d_i]\
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Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.
By DataStellar Co., Ltd
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.