CHRONIC ALCOHOLIC HEPATITIDES
\kɹˈɒnɪk ˌalkəhˈɒlɪk hˈɛpɐtˌɪta͡ɪdz], \kɹˈɒnɪk ˌalkəhˈɒlɪk hˈɛpɐtˌɪtaɪdz], \k_ɹ_ˈɒ_n_ɪ_k ˌa_l_k_ə_h_ˈɒ_l_ɪ_k h_ˈɛ_p_ɐ_t_ˌɪ_t_aɪ_d_z]\
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An acute or chronic degenerative and inflammatory lesion of the liver in the alcoholic which is potentially progressive though sometimes reversible. It does not necessarily include steatosis, fibrosis, or cirrhosis of alcoholics, although it is frequently associated with these conditions. It is characterized by liver cell necrosis, infiltration by polymorphonuclear leukocytes and lymphocytes, and Mallory bodies. The morphologic changes of chronic alcoholic hepatitis are not likely to be confused with chronic hepatitis (HEPATITIS, CHRONIC).
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.