CHOLINERGIC RECEPTORS
\kˌɒlɪnˈɜːd͡ʒɪk ɹɪsˈɛptəz], \kˌɒlɪnˈɜːdʒɪk ɹɪsˈɛptəz], \k_ˌɒ_l_ɪ_n_ˈɜː_dʒ_ɪ_k ɹ_ɪ_s_ˈɛ_p_t_ə_z]\
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Cell surface proteins that bind acetylcholine with high affinity and trigger intracellular changes influencing the behavior of cells. Cholinergic receptors are divided into two major classes, muscarinic and nicotinic, based originally on their affinity for nicotine and muscarine. Each group is further subdivided based on pharmacology, location, mode of action, and/or molecular biology.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.