CHO CELLS
\sˌiːˌe͡ɪt͡ʃˈə͡ʊ sˈɛlz], \sˌiːˌeɪtʃˈəʊ sˈɛlz], \s_ˌiː__ˌeɪ_tʃ_ˈəʊ s_ˈɛ_l_z]\
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Cell line derived from the ovary of the Chinese hamster, Cricetulus griseus. The species is a favorite for cytogenetic studies because of its small chromosome number. The cell line has provided model systems for the study of genetic alterations in cultured mammalian cells.
By DataStellar Co., Ltd
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.