CHLORIMIPRAMINE
\klˌɔːɹɪmˈɪpɹɐmˌiːn], \klˌɔːɹɪmˈɪpɹɐmˌiːn], \k_l_ˌɔː_ɹ_ɪ_m_ˈɪ_p_ɹ_ɐ_m_ˌiː_n]\
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A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.
By DataStellar Co., Ltd
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.