CHERCHEVSKI'S DISEASE

\t͡ʃɜːʃˈɛvskɪz dɪzˈiːz], \t‍ʃɜːʃˈɛvskɪz dɪzˈiːz], \tʃ_ɜː_ʃ_ˈɛ_v_s_k_ɪ_z d_ɪ_z_ˈiː_z]\

Definitions of CHERCHEVSKI'S DISEASE

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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