CAVERNOUS HEMANGIOMA
\kˈavənəs hˌɛmɐŋɡɪˈə͡ʊmə], \kˈavənəs hˌɛmɐŋɡɪˈəʊmə], \k_ˈa_v_ə_n_ə_s h_ˌɛ_m_ɐ_ŋ_ɡ_ɪ__ˈəʊ_m_ə]\
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A vascular tumor preponderantly composed of large dilated blood vessels, often containing large amounts of blood, occurring in the skin, subcutaneously, or both, and also in many viscera, particularly the liver, spleen, pancreas, and sometimes the brain. The typical superficial lesions are bright to dark red in color; deep lesions have a blue color. A cavernous hemangioma in the skin extends more deeply than a capillary hemangioma and is less likely to regress spontaneously. (Dorland, 27th ed; from Stedman, 25th ed)
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.