CARDIOTOXIN VII 4
\kˈɑːdɪˌə͡ʊtəksˌɪn ɹˌə͡ʊmən sˈɛvən fˈɔː], \kˈɑːdɪˌəʊtəksˌɪn ɹˌəʊmən sˈɛvən fˈɔː], \k_ˈɑː_d_ɪ__ˌəʊ_t_ə_k_s_ˌɪ_n ɹ_ˌəʊ_m_ə_n_ s_ˈɛ_v_ə_n f_ˈɔː]\
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Most abundant proteins in cobra (Naja of the Elapids) venom; basic polypeptides of 57 to 62 amino acids with four disulfide bonds and a molecular weight of less than 7000; causes skeletal and cardiac muscle contracture, interferes with neuromuscular and ganglionic transmission, depolarizes nerve, muscle and blood cell membranes, thus causing hemolysis. Synonyms: cobramine A; cobramine B; cobra cytotoxin; gamma toxin; membrane-active polypeptide.
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Procollagen Proline Dioxygenase
- mixed-function oxygenase that catalyzes hydroxylation prolyl-glycyl-containing-peptide, usually in protocollagen, hydroxyprolylglycyl-peptide. The enzyme utilizes molecular oxygen with a concomitant oxidative decarboxylation of 2-oxoglutarate to succinate. EC 1.14.11.2.