CARBONIC ANHYDRASE C
\kɑːbˈɒnɪk ˈanha͡ɪdɹˌe͡ɪz sˈiː], \kɑːbˈɒnɪk ˈanhaɪdɹˌeɪz sˈiː], \k_ɑː_b_ˈɒ_n_ɪ_k ˈa_n_h_aɪ_d_ɹ_ˌeɪ_z s_ˈiː]\
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A cytosolic carbonic anhydrase isoenzyme found widely distributed in cells of almost all tissues. Deficiencies of carbonic anhydrase II produce a syndrome characterized by OSTEOPETROSIS, renal tubular acidosis (ACIDOSIS, RENAL TUBULAR) and cerebral calcification. EC 4.2.1.-
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.