CALCITONIN GENE RELATED PEPTIDE II
\kˈalsɪtˌɒnɪn d͡ʒˈiːn ɹɪlˈe͡ɪtɪd pˈɛpta͡ɪd ɹˌə͡ʊmən tˈuː], \kˈalsɪtˌɒnɪn dʒˈiːn ɹɪlˈeɪtɪd pˈɛptaɪd ɹˌəʊmən tˈuː], \k_ˈa_l_s_ɪ_t_ˌɒ_n_ɪ_n dʒ_ˈiː_n ɹ_ɪ_l_ˈeɪ_t_ɪ_d p_ˈɛ_p_t_aɪ_d ɹ_ˌəʊ_m_ə_n_ t_ˈuː]\
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Calcitonin gene-related peptide. A 37-amino acid peptide derived from the calcitonin gene. It occurs as a result of alternative processing of mRNA from the calcitonin gene. The neuropeptide is widely distributed in neural tissue of the brain, gut, perivascular nerves, and other tissue. The peptide produces multiple biological effects and has both circulatory and neurotransmitter modes of action. In particular, it is a potent endogenous vasodilator.
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Procollagen Proline Dioxygenase
- mixed-function oxygenase that catalyzes hydroxylation prolyl-glycyl-containing-peptide, usually in protocollagen, hydroxyprolylglycyl-peptide. The enzyme utilizes molecular oxygen with a concomitant oxidative decarboxylation of 2-oxoglutarate to succinate. EC 1.14.11.2.