CACHECTIN TUMOR NECROSIS FACTOR
\kˈaʃɪktˌɪn tjˈuːmə nɛkɹˈə͡ʊsɪs fˈaktə], \kˈaʃɪktˌɪn tjˈuːmə nɛkɹˈəʊsɪs fˈaktə], \k_ˈa_ʃ_ɪ_k_t_ˌɪ_n t_j_ˈuː_m_ə n_ɛ_k_ɹ_ˈəʊ_s_ɪ_s f_ˈa_k_t_ə]\
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Serum glycoprotein produced by activated macrophages and other mammalian mononuclear leukocytes. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share two receptors.
By DataStellar Co., Ltd
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.
Nearby Words
- cachectic fever
- cachectic infantilism
- cachectical
- cachectin
- cachectin receptors
- Cachectin Tumor Necrosis Factor
- cachelcoma
- cachemere
- cachemia
- cachen-laguen
- cachepot