Definitions of C4 Binding Protein

  1. A major adhesion- associated heterodimer molecule expressed by human monocytes, granulocytes, NK cells, and some lymphocytes. The alpha subunit is the CD11c antigen ( also called Leu- M5), a surface antigen expressed on some myeloid cells. The beta subunit is the CD18 antigen ( ANTIGENS, CD18). The complement 4- binding protein has been shown to play an important role in cell- cell and cell- substrate adhesive interactions.