C3 NEPHRITIC FACTOR
\sˈiː θɹˈiː nɛfɹˈɪtɪk fˈaktə], \sˈiː θɹˈiː nɛfɹˈɪtɪk fˈaktə], \s_ˈiː θ_ɹ_ˈiː n_ɛ_f_ɹ_ˈɪ_t_ɪ_k f_ˈa_k_t_ə]\
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A magnesium-dependent IMMUNOGLOBULIN G autoantibody found in serum of patients with chronic mesangioproliferative hypocomplementemic glomerulonephritis. It causes inactivation of C3 in the alternate pathway by cleaving C3 into two inactive fragments, C3c and C3d, instead of the normal C3b.
By DataStellar Co., Ltd
Word of the day
Quinones
- Hydrocarbon rings which contain two moieties position. They can be substituted in any position except at the ketone groups.
Nearby Words
- c2man
- c3
- c3 activator
- c3 c5 convertase
- c3 convertase
- C3 Nephritic Factor
- c3 proactivator
- c36278ba
- c386
- c3a
- c3b