C ERBB 3 PROTEIN
\sˈiː ˈɜːb bˈiː θɹˈiː pɹˈə͡ʊtiːn], \sˈiː ˈɜːb bˈiː θɹˈiː pɹˈəʊtiːn], \s_ˈiː_ ˈɜː_b b_ˈiː θ_ɹ_ˈiː p_ɹ_ˈəʊ_t_iː_n]\
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A cell surface protein-tyrosine kinase receptor that is specific for NEUREGULINS. It has extensive homology to and can heterodimerize with the EGF Receptor (RECEPTOR, EPIDERMAL GROWTH FACTOR) and the erbB-2 receptor (RECEPTOR, ERBB-2). Overexpression of the erbB-3 receptor is associated with tumorigenesis. EC 2.7.11.-.
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Word of the day
Procollagen Proline Dioxygenase
- mixed-function oxygenase that catalyzes hydroxylation prolyl-glycyl-containing-peptide, usually in protocollagen, hydroxyprolylglycyl-peptide. The enzyme utilizes molecular oxygen with a concomitant oxidative decarboxylation of 2-oxoglutarate to succinate. EC 1.14.11.2.