C ABL PROTO ONCOGENES
\sˈiː ˈabə͡l pɹˈə͡ʊtə͡ʊ ˈɒnkə͡ʊd͡ʒˌiːnz], \sˈiː ˈabəl pɹˈəʊtəʊ ˈɒnkəʊdʒˌiːnz], \s_ˈiː_ ˈa_b_əl p_ɹ_ˈəʊ_t_əʊ ˈɒ_n_k_əʊ_dʒ_ˌiː_n_z]\
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Retrovirus-associated DNA sequences (abl) originally isolated from the Abelson murine leukemia virus (Ab-MuLV). The proto-oncogene abl (c-abl) codes for a protein that is a member of the tyrosine kinase family. The human c-abl gene is located at 9q34.1 on the long arm of chromosome 9. It is activated by translocation to bcr on chromosome 22 in chronic myelogenous leukemia.
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