C ABL PROTEINS
\sˈiː ˈabə͡l pɹˈə͡ʊtiːnz], \sˈiː ˈabəl pɹˈəʊtiːnz], \s_ˈiː_ ˈa_b_əl p_ɹ_ˈəʊ_t_iː_n_z]\
Sort: Oldest first
-
Non-receptor tyrosine kinases encoded by the c-abl gene. They are distributed in both the cytoplasm and the nucleus. c-Abl plays a role in normal hematopoiesis especially of the myeloid lineage. Oncogenic transformation of c-abl arises when specific N-terminal amino acids are deleted, releasing the kinase from negative regulation.
By DataStellar Co., Ltd
Word of the day
SQ10,643
- A serotonin antagonist with limited antihistaminic, anticholinergic, and immunosuppressive activity.