C TRK PROTEIN
\sˈiː tˌiːˌɑːkˈe͡ɪ pɹˈə͡ʊtiːn], \sˈiː tˌiːˌɑːkˈeɪ pɹˈəʊtiːn], \s_ˈiː t_ˌiː__ˌɑː_k_ˈeɪ p_ɹ_ˈəʊ_t_iː_n]\
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A protein-tyrosine kinase receptor that is specific for NERVE GROWTH FACTOR; NEUROTROPHIN 3; neurotrophin 4, neurotrophin 5. It plays a crucial role in pain sensation and thermoregulation in humans. Gene mutations that cause loss of receptor function are associated with congenital insensitivity to pain with anhidrosis, while gene rearrangements that activate the protein-tyrosine kinase function are associated with tumorigenesis. EC 2.7.11.-.
By DataStellar Co., Ltd
Word of the day
SQ10,643
- A serotonin antagonist with limited antihistaminic, anticholinergic, and immunosuppressive activity.