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Definitions of c mos Proto Oncogenes

  1. Retrovirus- associated DNA sequences ( mos) originally isolated from the Moloney murine sarcoma virus ( Mo- MSV). The proto- oncogene mos ( c- mos) codes for a protein which is a member of the serine kinase family. There is no evidence as yet that human c- mos can become transformed or has a role in human cancer. However, in mice, activation can occur when the retrovirus- like intracisternal A- particle inserts itself near the c- mos sequence. The human c- mos gene is located at 8q22 on the long arm of chromosome 8.
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